TODAY今日发布HerzEarlyRecent,Sept04,今日发布01篇CardiovascDrugsTherEarlyRecent,Sept04,今日发布01篇ClinicalCardiologyEarlyRecent,Sept04,今日发布01篇JNuclCardiolEarlyRecent,Sept04,今日发布01篇JAMAEarlyRecent,Sept04,今日发布03篇ESCHeartFailureEarlyRecent,Sept04,今日发布02篇EuropeanJournalofHeartFailureSept05,:22(s1),i-vi,2今日发布03篇HeartandVesselsEarlyRecent,Sept05,今日发布01篇HeartFailRevEarlyRecent,Sept05,今日发布01篇RECOMMEND推荐阅读01大出血风险患者的大面积肺栓塞:医院成功使用超声辅助导管溶栓的病例系列JThrombThrombolysisArticleJingzhouHe,BenjaminClayton,etc.昨天22:11Massivepulmonaryembolism(PE),characterisedbyprofoundarterialhypotension,isalife-threateningemergencywitha90-daymortalityofover50%.Systemicthrombolysiscansignificantlyreducetheriskofdeathorcardiovascularcollapseinthesepatients,byaround50%,butthesebenefitsareoffsetbyafivefoldincreasedriskofintracranialhaemorrhageandmajorbleeding,whichmaylimititsuseinpatientsathighriskofcatastrophichaemorrhage.Wedescribeacaseseriesof3patientspresentingwithmassivePE,eachwithextremeriskofbleedingandcontra-indicationtosystemicthrombolysis,treatedsuccessfullywithultrasound-assisted,catheterdirectedthrombolysis(U-ACDT).OurexperienceofthisnoveltechniqueusingtheEkoSonicEndovascularSystem(Ekos,BTG,London,UK)oncarefullyselectedpatientshasdemonstratedthepotentialtoimproveclinicalstatusinshockedpatients,withminimalbleedrisk.TherehavebeenseveralclinicalstudiesevaluatingtheEkossystem.BoththeULTIMAandSEATTLEIIstudieshaveshownsignificantreductionsinRV/LVratiobyCTscanningwhen
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